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Once produced and packaged in Paris, these medicines were then sold in pharmacies in most major cities across France and exported to distributors across France and in over two dozen countries, who then marketed and sold the products

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Archived from the original on 15 July 2006

On the other hand, marked anatomical changes in filiform papillae may cause the patient to capture foreign matter and stimulate local microbial overgrowth, which results in the typical color changes seen in patients with this condition